https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:34159 -8; AUC: 0.909, CR: 72.7%). Conclusions: These results support the use of expression profiling in whole blood in the absence of more specific tissue types for investigations of metabolic disease. Using a pathway analysis approach it was possible to identify an enrichment of DEG into biological pathways that could be targeted for in vitro follow-up.]]> Wed 15 Dec 2021 16:10:14 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:11479 Wed 11 Apr 2018 16:22:04 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36077 Haemophilus influenzae is the most commonly identified bacteria. Haemophilus influenzae is divided into typeable and nontypeable (NTHi) strains based on the presence or absence of a polysaccharide capsule. While NTHi is a common commensal in the human nasopharynx, it is associated with considerable inflammation when it is present in the lower airways of COPD patients, resulting in morbidity due to worsening symptoms and increased frequency of COPD exacerbations. Treatment of lower airway NTHi infection with antibiotics, though successful in the short term, does not offer long-term protection against reinfection, nor does it change the course of the disease. Hence, there has been much interest in the development of an effective NTHi vaccine. This review will summarize the current literature concerning the role of NTHi infections in COPD patients and the consequences of using prophylactic antibiotics in patients with COPD. There is particular focus on the rationale, findings of clinical studies and possible future directions of NTHi vaccines in patients with COPD.]]> Wed 09 Feb 2022 15:54:02 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:26762 Thu 24 Mar 2022 11:35:38 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7339 Sat 24 Mar 2018 08:35:12 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:2000 Sat 24 Mar 2018 08:28:59 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:11262 Sat 24 Mar 2018 08:10:52 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19173 Sat 24 Mar 2018 07:52:17 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5515 Sat 24 Mar 2018 07:46:42 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5280 Sat 24 Mar 2018 07:46:32 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:207 Sat 24 Mar 2018 07:43:08 AEDT ]]>